A retrospective study of hepatitis C virus (HCV) transmission by transfusion was conducted in Orebro county.
Out of the 7900 active, registered blood donors, 21 repeatedly anti-HCV reactive (RIBA 2 positive or indeterminate) donors were diagnosed.
Their 84 recipients from January 1990 through June 1992 were identified and 41 (49'%) were alive in December 1992.
A total of 13 anti-HCV reactive (RIBA 2 positive or indeterminate) were diagnosed in 39 investigated recipients.
Of these II were previously undiagnosed, and seven were HCV RNA-positive.
In the donor population 1.03% were anti-HCV-positive by ELISA, but only 0.09% were RIBA and HCV RNA-positive.
In 1990,0.06% of the blood components came from the HCV RNA-positive donors, and none during the first 6 months of 1992.
In order to identify transfusion-transmitted HCV infections that took place before the introduction of tests for anti-HCV antibodies, patients with a history of transfusion and symptoms and signs of liver dysfunction or damage should be thoroughly tested.
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Transmission, Virus hépatite C, Flaviviridae, Virus, Suède, Europe, Transfusion, Sang, Homme, Epidémiologie, Appareil digestif pathologie, Foie pathologie, Hygiène
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Transmission, Hepatitis C virus, Flaviviridae, Virus, Sweden, Europe, Transfusion, Blood, Human, Epidemiology, Digestive diseases, Hepatic disease, Hygiene
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0008517
Code Inist : 002B05C02G. Création : 01/03/1996.