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  1. Transmission of hepatitis C virus by transfusion in Orebro county, Sweden, 1990-1992.

    Article - En anglais

    A retrospective study of hepatitis C virus (HCV) transmission by transfusion was conducted in Orebro county.

    Out of the 7900 active, registered blood donors, 21 repeatedly anti-HCV reactive (RIBA 2 positive or indeterminate) donors were diagnosed.

    Their 84 recipients from January 1990 through June 1992 were identified and 41 (49'%) were alive in December 1992.

    A total of 13 anti-HCV reactive (RIBA 2 positive or indeterminate) were diagnosed in 39 investigated recipients.

    Of these II were previously undiagnosed, and seven were HCV RNA-positive.

    In the donor population 1.03% were anti-HCV-positive by ELISA, but only 0.09% were RIBA and HCV RNA-positive.

    In 1990,0.06% of the blood components came from the HCV RNA-positive donors, and none during the first 6 months of 1992.

    In order to identify transfusion-transmitted HCV infections that took place before the introduction of tests for anti-HCV antibodies, patients with a history of transfusion and symptoms and signs of liver dysfunction or damage should be thoroughly tested.

    Mots-clés Pascal : Hépatite virale C, Virose, Infection, Transmission, Virus hépatite C, Flaviviridae, Virus, Suède, Europe, Transfusion, Sang, Homme, Epidémiologie, Appareil digestif pathologie, Foie pathologie, Hygiène

    Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Transmission, Hepatitis C virus, Flaviviridae, Virus, Sweden, Europe, Transfusion, Blood, Human, Epidemiology, Digestive diseases, Hepatic disease, Hygiene

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 96-0008517

    Code Inist : 002B05C02G. Création : 01/03/1996.