1 Available literature dealing with neuropsychapathological changes after exposure to organophosphate insecticides is reviewed. 2 Subacute neurological sequelae following acute organophosphate intoxication include the'intermediate syndrome'probably a myopathy elicited by excess acetylcholine, and the'organophosphate-induced delayed neuropathy' (OPIDN), which is caused by particularly neurotoxic organophosphates that inhibit neuropathy target esterase. 3 Long-term toxic effects affecting behaviour as well as mental and visual functions are occasionally observed after exposure to high doses of organophosphates with repeated acute, clinically significant intoxications. 4 The available data do not indicate that asymptomatic exposure to organophosphates is connected with an increasing risk of delayed or permanent neuropsychopathological effects.
Mots-clés Pascal : Organophosphoré, Toxicité retardée, Système nerveux pathologie, Trouble comportement, Polluant, Environnement, Homme, Insecticide, Pesticide, Arme chimique, Article synthèse
Mots-clés Pascal anglais : Organophosphorus compounds, Delayed toxicity, Nervous system diseases, Behavioral disorder, Pollutant, Environment, Human, Insecticide, Pesticides, Chemical warfare agent, Review
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0008172
Code Inist : 002B03L06. Création : 01/03/1996.