Tobacco-specific nitrosamines in some Nigerian cigarettes.
Ten popular brands of cigarettes on the Nigerian market were analyzed for tobacco-specific nitrosamines (TSNA) in tobacco and in mainstream smoke, as well as nitrate in tobacco.
TSNA was analyzed using a gas chromatography/thermal energy analyzer (GC-TEA), while nitrate was determined spectrophotometrically as nitrite following on-line reduction with copper, diozatization with sulfanilamide and coupling with N- (1-naphthyl) ethylene diamine to form an azo dye.
In mainstream smoke, the concentration of NNN, NAB/NAT and NNK were respectively, between 8 and 90 ng, 10 and 65 ng, and between 15 and 72 ng/cigarette.
Preformed NNN ranged between 64 and 565 ng/cigarette, while preformed NAB/NAT and NNK ranged respectively from 109 to 476 ng/cigarette, and from 55 to 317 ng/cigarette.
Nitrate levels ranged between 1.5 and 6.1 mg/g tobacco.
In general, the results indicate that the TSNA content of Nigerian cigarettes are within the range found for European and American cigarettes.
Mots-clés Pascal : Tabac, Cigarette, Niger, Afrique, Nitrosamine, Fumée courant primaire, Carcinogène, Nitrate, Analyse quantitative, Chromatographie phase gazeuse, Facteur risque, Butan-1-one(4-[méthyl nitroso amino]-1-[3-pyridyl]), NNK
Mots-clés Pascal anglais : Tobacco, Cigarette, Niger, Africa, Nitrosamine, Mainstream smoke, Carcinogen, Nitrates, Quantitative analysis, Gas chromatography, Risk factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0003633
Code Inist : 002B03E. Création : 01/03/1996.