There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America.
We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases.
These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.
Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Monde Ouest, Epidémiologie, Homme, Immunopathologie, Immunodéficit, Cytogénétique, Soustype E
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Western countries, Epidemiology, Human, Immunopathology, Immune deficiency, Cytogenetics
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 96-0003442
Code Inist : 002B06D01. Création : 01/03/1996.