The prevalence of positive skin-prick test reactions to ammonium persulphate and potassium persulphate (1% and 5% solutions) was tested in a cross-sectional study on 52 employees of a company producing persulphates after a case of « persulphate asthma » was observed.
A random test of 13 persons without occupational exposure to persulphates served as controls ; among them all the skin-prick test reactions were negative.
Eight company employees showed a positive skin-prick test reaction to at least one of the persulphate solutions tested.
Employees showed lower lung function results with a positive prick test reaction than did employees with a negative result.
The positive skin-prick reactions correspond well to the anamnestic data and indicate a possible relationship to obstructive ventilation disorders.
The results therefore suggest an IgE-induced, allergic pathomechanism of « persulphate asthma » triggered by persulphates.
Mots-clés Pascal : Ammonium Peroxomonosulfate, Potassium Peroxomonosulfate, Exposition professionnelle, Asthme, Homme, IgE, Médecine travail, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie
Mots-clés Pascal anglais : Ammonium Peroxomonosulfates, Potassium Peroxomonosulfates, Occupational exposure, Asthma, Human, IgE, Occupational medicine, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0592615
Code Inist : 002B03L06. Création : 01/03/1996.