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  1. Evidence against an increased risk of Helicobacter pylori infecton in dentists : a serological and salivary study.

    Article - En anglais

    Background 

    An oral-to-oral route of transmission of Helicobacterpylori infection has been postulated, which is supported by the observation that H. pylori is present in the saliva and in dental plaque.

    On the basis of this assumption, an increased risk of H. pylori infection among dentists was postulated.

    Method 

    Serum and salivary H. pylori immunoglobulin (Ig) G antibodies were measured in a group of practising dentists.

    For comparison we also studied a group of controls from the same urban area matched for age, sex, smoking habits, alcohol and non-steroidal anti-inflammatory drug consumption, and history of dyspepsia.

    Results 

    There was no significant difference in serum H. pylori IgG antibodies titres between dentists and controls [optical density (OD) 0.991 ± 0.588 versus 1.025 ± 0.591, respectively]. Salivary H. pylori IgG were 0.693 ± 0.726 and 0.661 ± 0.614 OD in the dentists and control groups, respectively.

    The frequency of H. pylori-seropositive subjects did not differ between the two groups [22 out of 39 (56%) versus 46 out of 71 (64%) ]. A positive saliva assay was found in 23 out of 39 (59%) dentists and in 44 out of 71 (62%) controls.

    The odds ratio for a dentist being H. pylori-positive was 0.7 (95% confidence interval 0.3-1.7) by serology and 0.9 (95% confidence interval 0.4-2.1) by salivary antibody assay.

    Conclusion 

    The data of this study do not support the concept that dentists are a high-risk group for H. pylori infection.

    Mots-clés Pascal : Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Salive, Plaque dentaire, Facteur risque, Transmission, Exposition professionnelle, Dentiste, Etude statistique, Homme

    Mots-clés Pascal anglais : Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Saliva, Dental plaque, Risk factor, Transmission, Occupational exposure, Dentist, Statistical study, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0573964

    Code Inist : 002B05B02F. Création : 01/03/1996.