Disclosure of trauma and immune response to a hepatitis B vaccination program.
This study investigated whether emotional expression of traumatic experiences influenced the immune response to a hepatitis B vaccination program.
Forty medical students who tested negative for hepatitis B antibodies were randomly assigned to write about personal traumatic events or control topics during 4 consecutive daily sessions.
The day after completion ofthe writing, participants were given their first hepatitis B vaccination, with booster injections at I and 4 months after the writing.
Blood was collected before each vaccination and at a 6-month follow-up.
Compared with the control group, participants in the emotional expression group showed significantly higher antibody levels against hepatitis B at the 4 and 6-month follow-up periods.
Other immune changes evident immediately after writing were significantly lower numbers of circulating T helper lymphocytes and basophils in the treatment group.
The finding that a writing intervention influences immune response provides further support for a link between emotional disclosure and health.
Mots-clés Pascal : Stress, Traumatisme, Ouverture personnelle, Emotion émotivité, Cognition, Immunomodulation, Réponse immune, Coping, Vaccination, Hépatite virale B, Virose, Infection, Prévention, Programme sanitaire, Adulte, Homme, Expression émotionnelle, Psychoneuroimmunologie
Mots-clés Pascal anglais : Stress, Trauma, Self disclosure, Emotion emotionality, Cognition, Immunomodulation, Immune response, Coping, Vaccination, Viral hepatitis B, Viral disease, Infection, Prevention, Sanitary program, Adult, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0565833
Code Inist : 002A26N03A. Création : 01/03/1996.