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  1. An ecological study of diet and lung cancer in the South Pacific.

    Article - En anglais

    Incidence rates of lung cancer have been markedly lower for Fiji than for other South Pacific countries, despite similar rates of smoking.

    We conducted population-based surveys in several island nations of the South Pacific (Cook Islands, Fiji, Tahiti and New Caledonia) and used data from Caucasian, Japanese, Hawaiian, Filipino and Chinese controls in a case-control study of lung cancer in Hawaii to investigate the role of diet in explaining differences in lung cancer incidence among 20 ethnic-sex groups.

    In a stepwise linear regression of lung cancer rates on smoking, diet and other variables, smoking, as expected, explained the majority (61%) of the variability in incidence.

    However, several dietary components also explained significant portions of the variance.

    Lutein intake explained 14% and vitamin E intake, cholesterol intake and height explained 5-7% each of the remaining variance in incidence.

    Associations with lutein and vitamin E were inverse, whereas those with cholesterol and height were direct.

    Dietary bêta-carotene intake was not associated with lung cancer incidence.

    These ecological data provide evidence for a protective effect of lutein against lung cancer.

    A protective effect of dietary vitamin E and a risk-enhancing effect of dietary cholesterol are also suggested.

    Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Incidence, Epidémiologie, Lutéine, alpha-Tocophérol, Vitamine, Cholestérol, Régime alimentaire, Iles Océan Pacifique, Océan Pacifique Sud, Océan Pacifique, Homme, Poumon pathologie, Bronche pathologie, Appareil respiratoire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Incidence, Epidemiology, Lutein, alpha-Tocopherol, Vitamin, Cholesterol, Diet, Pacific Ocean Islands, South Pacific, Pacific Ocean, Human, Lung disease, Bronchus disease, Respiratory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0549444

    Code Inist : 002B11A. Création : 01/03/1996.