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  1. Comparison of methods of estimating the mother-to-child transmission rate of human immunodeficiency virus type 1 (HIV-1).

    Article - En anglais

    Four methods of estimating mother-to-child transmission rates of human immunodeficiency virus type 1 (HIV-1), based on the 1992 Ghent workshop, were compared in a multicenter New York City prospective cohort study in 1986-1992.

    Of 833 infants born to women at risk of HIV-1 infection, 388 were born HIV-1 seropositive and 445 were HIV-1 seronegative.

    The four methods, the Antibody Only, Indirect, Direct, and Virologic Methods, yielded transmission rate estimates of 19-25%, classifying 59-89% of the cohort.

    Estimation based on persistence of HIV-1 antibody and clinical assessment yielded transmission rates similar to those methods that incorporated virologic testing.

    Am J Epidemiol 1995 ; 142 : 714-18.

    Mots-clés Pascal : Transmission, Mère, Enfant, Homme, SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Passage foetomaternel, Méthode étude, Etude comparative, Belgique, Europe, Epidémiologie, Dépistage, Méthode immunologique, Réaction chaîne polymérase, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Transmission, Mother, Child, Human, AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Fetomaternal transfer, Investigation method, Comparative study, Belgium, Europe, Epidemiology, Medical screening, Immunological method, Polymerase chain reaction, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0543692

    Code Inist : 002B06D01. Création : 01/03/1996.