Human immunodeficiency virus (HIV) incidence rates in India were estimated using a new method that accounts for follow-up bias.
Follow-up bias arises in epidemiologic cohort studies when the incidence rate among individuals who do and do not return for follow-up are different.
The new method combines data on the prevalence of p24 antigenemia among all those initially screened together with the longitudinal follow-up data on the subset of patients who returned for follow-up.
Using these methods, the current HIV incidence rate among patients attending sexually transmitted disease clinics in Pune, India, was 18.6% per year.
It was found that follow-up bias can cause significant underestimation in HIV incidence rates, perhaps by as much as 60%. These incidence estimates, together with other HIV seroprevalence studies, suggest the HIV epidemic in India is growing rapidly.
Am J Epidemiol 1995 ; 142 : 709-13.
Mots-clés Pascal : SIDA, Virose, Infection, Epidémiologie, Incidence, Méthode étude, Inde, Asie, Biais méthodologique, Etude longitudinale, Etude cohorte, Analyse statistique, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Epidemiology, Incidence, Investigation method, India, Asia, Methodological bias, Follow up study, Cohort study, Statistical analysis, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0543691
Code Inist : 002B06D01. Création : 01/03/1996.