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  1. Relationship of acute obstructive airway change to chronic (fixed) obstruction.

    Article - En anglais

    In this report of a 5-yr longitudinal study of workers at six cotton textile mills, exposure and across-shift FEV1 changes were evaluated as possible predictors of the annual change in FEV1 for yarn manufacturing workers.

    A total of 611 workers had three repeatable spirometric tests, over at least 3 yr, and at least one (average of three) across-shift test, while always working the same shift.

    The « same shift » criterion controlled for the effect of diurnal variation.

    Average exposure was determined from measures of lint-free elutriated cotton dust in combination with job histories.

    This study found a significant association between the acute and chronic effects of cotton dust exposure.

    Both exposure and across-shift change proved to be significant predictors of annual change, and excess annual declines in FEV1 were predicted even for exposures of 200 mug/m3 and across-shift drops in FEV1 of 200 ml.

    These results suggest that, to prevent dust-related chronic decline in lung function, current smokers should be excluded from yarn manufacturing work and exposure should be reduced below 200 mug/m3, to approximately 100 mug/m3.

    (Am J Respir Crit Care Med 1994 ; 149 : 584-90).

    Mots-clés Pascal : Bronchopneumopathie obstructive, Chronique, Poussière, Coton, Exposition professionnelle, Fonction respiratoire, Exploration, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Médecine travail

    Mots-clés Pascal anglais : Obstructive pulmonary disease, Chronic, Dust, Cotton, Occupational exposure, Lung function, Exploration, Human, Respiratory disease, Lung disease, Bronchus disease, Occupational medicine

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    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0539213

    Code Inist : 002B11B. Création : 01/03/1996.