The relationship of socioeconomic status to the risk of aplastic anaemia was evaluated in a case-control study conducted in Bangkok and two rural regions of Thailand (Khonkaen and Songkla).
Among 152 cases and 921 controls there were significant trends of increasing risk with decreasing years of education (P=0.01) and total household income (P=0.0001), after control for confounding.
The relative risk estimate for those with monthly incomes of<1500 baht (about $60 U.S.) was 3.9 (95% confidence interval 2.1-7.3) compared to those with monthly incomes of at least 5000 baht (about $200).
The pattern of increasing risk with decreasing income was observed in all three regions, with significant trends in Bangkok (P=0.004) and Khonkaen (P=0.003).
This finding may partly explain the high incidence of aplastic anaemia in Thailand.
Low socioeconomic status may be a surrogate for one or more environmental factors that could cause aplastic anaemia, such as infectious pathogens or toxic exposures.
Mots-clés Pascal : Anémie aplasique, Facteur risque, Epidémiologie, Statut socioéconomique, Thaïlande, Asie, Homme, Hémopathie, Etude cas témoin
Mots-clés Pascal anglais : Aplastic anemia, Risk factor, Epidemiology, Socioeconomic status, Thailand, Asia, Human, Hemopathy, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0530546
Code Inist : 002B19A01. Création : 01/03/1996.