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  1. Divergent racial trends in mortality from systemic lupus erythematosus.

    Article - En anglais

    Objective

    To compare trends in mortality from systemic lupus erythematosus (SLE) between black and white females in the United States.

    Methods

    Analysis of nationwide cause of death data collected by the National Center for Health Statistics, 1968 to 1991.

    Results

    During the latter half of the 1968-91 period, trends in SLE mortality for black and white women under age 45 diverged and racial differences in total mortality from SLE widened.

    Among white females, total SLE mortality has been stable since the late 1970s at a mean annual rate of 4.6 deaths per million.

    This stability results from a balance between declining risk among whites under age 45 and increasing in those beyond 55.

    Among blacks, total mortality has risen more than 30% since the late 1970s to a mean annual rate of 18.7 per million.

    This increase results from a combination of constant risk in black females under 45 and rising risk in women over 55.

    Conclusion

    Trends for whites are consistent with a shift in mortality from younger to older women.

    This shift can be explained by longer postdiagnosis survival resulting from improved clinical management of SLE.

    The trends for blacks imply higher prevalence of SLE among black females than previously recognized and/or the existence of some impediment to young black females sharing in the full benefits of effective treatment.

    Mots-clés Pascal : Lupus érythémateux, Disséminé, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Mortalité, Etude comparative, Caucasoïde, Négroïde, Race, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie

    Mots-clés Pascal anglais : Lupus erythematosus, Disseminated, Human, Female, United States, North America, America, Epidemiology, Mortality, Comparative study, Caucasoid, Negroid, Race, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0528561

    Code Inist : 002B07. Création : 01/03/1996.