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  1. The new chemicals process at the Environmental Protection Agency (EPA) : structure-activity relationships for hazard identification and risk assessment.

    Article, Communication - En anglais

    1993 Decision support methodologies international workshop. Atlanta GA USA, 1993/10/18.

    Section 5 of the Toxic Substances Control Act (TSCA) does not require any toxicity testing as a prerequisite for submission of a Premanufacturing Notice (PMN) for a new chemical.

    In order to compensate for the lack of actual test data, a process involving structure-activity relationships (SAR) for assessing hazard potential was constructed.

    The hazard assessment is then coupled with an estimation of potential exposure to determine potential risk.

    This process involves the use of multiple interdisciplinary teams that work within a 90-day time frame to complete approximately 2000 risk assessments per year.

    Mots-clés Pascal : Composé chimique, Etats Unis, Amérique du Nord, Amérique, Organisme réglementation, Protection environnement, Relation structure activité, Evaluation, Risque, Homme, Toxicité

    Mots-clés Pascal anglais : Chemical compound, United States, North America, America, Regulatory institution, Environmental protection, Structure activity relation, Evaluation, Risk, Human, Toxicity

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0525918

    Code Inist : 002B03A. Création : 01/03/1996.