To investigate the possible association between changes in coffee consumption and serum cholesterol levels, information was obtained from 2109 healthy nonsmokers aged 25-65 years at two clinic visits to a preventive medical center between 1987 and 1991 (mean interval between visits : 16.7 months).
After adjusting for age and changes in other potential confounders, about 2 mg/dl total cholesterol increase was associated with an increase of one cup of regular coffee per day (p<0.001).
A dose-response was found among those who decreased regular coffee consumption, those who continued the same dose, and those who increased consumption.
The same trend was observed among those who quit drinking regular coffee, those who never drank coffee, and those who started to drink coffee.
No change in cholesterol level was found among those continuing to consume the same quantity of regular coffee compared to those who never drank coffee.
The change in cholesterol level was not related to consumption of decaffeinated coffee, regular tea, decaffeinated tea, or cola with caffeine.
To our knowledge, this is the first follow-up study correlating change in coffee consumption with change in serum cholesterol in a large group of men and women.
Mots-clés Pascal : Café, Boisson stimulante, Epidémiologie, Toxicité, Taux, Cholestérol, Sérum, Homme, Relation dose réponse, Consommation alimentaire, Etats Unis, Amérique du Nord, Amérique, Lipide
Mots-clés Pascal anglais : Coffee, Stimulative beverage, Epidemiology, Toxicity, Rate, Cholesterol, Serum, Human, Dose activity relation, Food intake, United States, North America, America, Lipids
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0514467
Code Inist : 002B03H. Création : 01/03/1996.