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  1. Congenital healed cleft hip.

    Article - En anglais

    Congenital « healed » cleft lip (CHCL) is an unusual anomaly including a paramedian « scar » of the upper lip, which appears as if a typical cleft lip has been corrected in utero.

    The CHCL is frequently associated with an ipsilateral notch in the vermilion, and « collapsed » nostril.

    Twenty-five CHCL cases are presented, eighteen of which were an isolated malformation found among the 3,950,715 births examined in two similar birth defect registries : ECEMC in Spain and ECLAMC in Latin America.

    Like open cleft lip, of which it seems to be a variant, CHCL is most frequently seen among males (14/18 isolated cases), it preferentially affects the left side (10/18 cases), and it segregated together with cleft lip in one family.

    The five CHCL cases with other congenital anomalies included : two cases with hydrocephalus, two VACTERL associations, and one atypical oblique facial cleft infant with single umbilical artery.

    CHCL may result from a defective fusion of the frontonasal and maxillary processes (before week 7 of embryonic life), or from a spontaneously repaired open cleft lip, later on.

    In either way, these cases heal with a visible scar, and the pre-occurrence of CHCL in two families suggests a familial predisposition to this phenomenon.

    Mots-clés Pascal : Fissure congénitale, Lèvre, Palais, Cicatrice, Congénital, Nourrisson, Homme, Epidémiologie, Espagne, Europe, Amérique Latine, Amérique, Stomatologie, Cavité buccale pathologie, Maladie congénitale, Malformation

    Mots-clés Pascal anglais : Cleft, Lip, Palate, Scar, Congenital, Infant, Human, Epidemiology, Spain, Europe, Latin America, America, Stomatology, Oral cavity disease, Congenital disease, Malformation

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0503704

    Code Inist : 002B10C02. Création : 01/03/1996.