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  1. Fulltext. Associations of peptic ulcer and gastric cancer with other diseases in US veterans.

    Article - En anglais

    Fulltext.

    Objectives

    The purpose of this study was to examine, through the database of the Department of Veterans Affairs, the joint occurrence of different diseases in individuals patients.

    Methods

    Patients with a diagnosis of gastric cancer, gastric ulcer, or duodenal ulcer were extracted from the 1987 through 1990 computer files.

    A random sample of patients from each annual file served as a control population.

    All previous discharges of each case or control patient between 1970 and 1990 were searched for the occurrence of hypertensive diseases or chronic diseases of the joints, lungs, pancreas, and liver.

    The relative frequencies of such diagnoses in case and control patients were compared by multivariate logistic regression.

    Results

    Gastric ulcer and duodenal ulcer, but not gastric cancer, were significantly associated with chronic diseases of the joints, lungs, pancreas, and liver.

    None of the three diagnoses showed and significant association with hypertensive diseases.

    Conclusions

    These relationships may reflect the influence of nonsteroidal anti-inflammatory drugs, smoking, and alcohol.

    They stress the importance of environmental risk factors other than Helicobacter pylori in terms of damage to the upper gastrointestinal mucosa.

    Mots-clés Pascal : Ulcère, Estomac, Tumeur maligne, Epidémiologie, Association, Homme, Ancien combattant, Etats Unis, Amérique du Nord, Amérique, Estomac pathologie, Appareil digestif pathologie

    Mots-clés Pascal anglais : Ulcer, Stomach, Malignant tumor, Epidemiology, Association, Human, Veteran, United States, North America, America, Gastric disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0500804

    Code Inist : 002B13B03. Création : 01/03/1996.