The objectives of the present study were to assess the impact of lactation on the folate status of adolescents and determine the effect of ingestion of a low-dose postpartum (PP) folic acid supplement on maternal folate and zinc status and milk composition.
Pregnant adolescents (aged 14-19 y ; n=71) were recruited ; those who initiated breast-feeding on delivery were randomly assigned to a folic acid supplement lactating (SL ; 300 mug/d, n=14) group or to a placebo lactating (PL ; n=15) group.
Subjects who initiated formula feeding were given a placebo (FF ; n=18).
Dietary intakes (two 24-h recalls) were recorded and blood and milk samples were collected at 4,8, and 12 wk PP.
Of the adolescents, 71%, 48%, 67%, and 60% had folate, iron, vitamin B-12, and zinc intakes, respectively, below their predicted requirements.
Despite this, most blood indexes were within normal ranges, probably reflecting the subjects'use of supplements during pregnancy.
Red blood cell (r=-0.49, P<0.05) and plasma (r=-0.42, P=0.08) folate concentrations were negatively correlated with milk zinc concentrations.
Mean red blood cell folate content declined between 4 and 12 wk PP among PL (31%) and FF (34%) subjects (P<0.05) but not among SL subjects.
Hence, 300 mug folic acid/d was sufficient to prevent a decline in blood folate values of these adolescents PP.
Mots-clés Pascal : Postpartum, Lactation, Régime alimentaire enrichi, Chimiothérapie, Folique acide, Etat nutritionnel, Folate, Zinc, Cyanocobalamine, Vitamine, Micronutriment, Nutrition, Adolescent, Homme, Femelle
Mots-clés Pascal anglais : Puerperium, Lactation, Supplemented diet, Chemotherapy, Folic acid, Nutritional status, Folate, Zinc, Cyanocobalamin, Vitamin, Micronutrient, Nutrition, Adolescent, Human, Female
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0499856
Code Inist : 002B29B. Création : 01/03/1996.