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  1. Fulltext. Postpartum folic acid supplementation of adolescents : impact on maternal folate and zinc status and milk composition.

    Article - En anglais


    The objectives of the present study were to assess the impact of lactation on the folate status of adolescents and determine the effect of ingestion of a low-dose postpartum (PP) folic acid supplement on maternal folate and zinc status and milk composition.

    Pregnant adolescents (aged 14-19 y ; n=71) were recruited ; those who initiated breast-feeding on delivery were randomly assigned to a folic acid supplement lactating (SL ; 300 mug/d, n=14) group or to a placebo lactating (PL ; n=15) group.

    Subjects who initiated formula feeding were given a placebo (FF ; n=18).

    Dietary intakes (two 24-h recalls) were recorded and blood and milk samples were collected at 4,8, and 12 wk PP.

    Of the adolescents, 71%, 48%, 67%, and 60% had folate, iron, vitamin B-12, and zinc intakes, respectively, below their predicted requirements.

    Despite this, most blood indexes were within normal ranges, probably reflecting the subjects'use of supplements during pregnancy.

    Red blood cell (r=-0.49, P<0.05) and plasma (r=-0.42, P=0.08) folate concentrations were negatively correlated with milk zinc concentrations.

    Mean red blood cell folate content declined between 4 and 12 wk PP among PL (31%) and FF (34%) subjects (P<0.05) but not among SL subjects.

    Hence, 300 mug folic acid/d was sufficient to prevent a decline in blood folate values of these adolescents PP.

    Mots-clés Pascal : Postpartum, Lactation, Régime alimentaire enrichi, Chimiothérapie, Folique acide, Etat nutritionnel, Folate, Zinc, Cyanocobalamine, Vitamine, Micronutriment, Nutrition, Adolescent, Homme, Femelle

    Mots-clés Pascal anglais : Puerperium, Lactation, Supplemented diet, Chemotherapy, Folic acid, Nutritional status, Folate, Zinc, Cyanocobalamin, Vitamin, Micronutrient, Nutrition, Adolescent, Human, Female

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0499856

    Code Inist : 002B29B. Création : 01/03/1996.