logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Frequency of sister chromatid exchange and hematological effects in pesticide-exposed greenhouse sprayers.

    Article - En anglais

    Objectives A cross-sectional study was conducted to investigate whether exposure to pesticides in greenhouses causes hemato-or genotoxic damage in sprayers.

    Methods The frequency of sister chromatid exchange (SCE) in cultured lymphocytes and the number of blood erythrocytes, leucocytes, and thrombocytes were studied among 134 greenhouse sprayers exposed to a complex mixture of almost 50 insecticides, fungicides, and growth regulators and among 157 referents.

    Results The hematological profiles did not differ between the exposed and unexposed groups.

    The SCE frequency was elevated in nonsmoking, but not in currently smoking sprayers when compared with the referents.

    There was a slight tendency towards an increased SCE frequency with decreasing degree of protection during pesticide applications.

    The frequency of pesticide applications, lifetime pesticide exposure, and inseason plasma-cholinesterase inhibition (as an estimate of current exposure to organophosphates and carbamates) did not influence the SCE frequency or any of the hematological parameters.

    Conclusions The present results suggest a genotoxic effect from combined subtoxic occupational pesticide exposure, whereas no hematogenic effects could be observed at the current exposure level.

    Mots-clés Pascal : Pesticide, Exposition professionnelle, Serre, Toxicité, Echange chromatide soeur, DNA, Hématologie, Epidémiologie, Danemark, Europe, Homme, Médecine travail

    Mots-clés Pascal anglais : Pesticides, Occupational exposure, Greenhouse, Toxicity, Sister chromatid exchange, DNA, Hematology, Epidemiology, Denmark, Europe, Human, Occupational medicine

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0498718

    Code Inist : 002B03G. Création : 01/03/1996.