To explore whether the characteristics of coal mine dust that predispose to chronic airways obstruction are the same as those associated with pneumoconiosis, mortality from the two diseases was compared in coal miners in 22 counties of England and Wales during 1979-80 and 1982-90.
The proportional mortality ratios (PMRs) for coal workers'pneumoconiosis varied from 135 (95% confidence interval (95% CI) 16-488) in Leicestershire to 3825 (95% CI 1538-7881) in South Glamorgan.
The PMRs for chronic bronchitis and emphysema were consistently higher than those in other occupations, but showed much less geographical variation and did not correlate geographically with those for pneumoco-niosis.
These findings indicate that the pathogenetic mechanisms by which coal mine dust causes chronic bronchitis and emphysema depend on different features of the dust from those producing pneumoconiosis.
Also, they suggest that current social security regulations in Britain, which require evidence of pneumoconiosis as a condition of compensation for chronic bronchitis and emphysema in coal miners, may discriminate unfairly against claimants from some regions.
Mots-clés Pascal : Royaume Uni, Europe, Mine, Charbon, Exposition professionnelle, Homme, Pneumoconiose, Emphysème, Bronchite, Chronique, Mortalité, Poussière, Epidémiologie, Médecine travail, Répartition géographique, Appareil respiratoire pathologie, Poumon pathologie, Indemnité dédommagement
Mots-clés Pascal anglais : United Kingdom, Europe, Mine, Coal, Occupational exposure, Human, Pneumoconiosis, Emphysema, Bronchitis, Chronic, Mortality, Dust, Epidemiology, Occupational medicine, Geographic distribution, Respiratory disease, Lung disease, Indemnity
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0496810
Code Inist : 002B03L03. Création : 01/03/1996.