The aim of this article was to summarize the epidemiologic studies on the possible impact of parental occupational exposure to lead or other metals on spontaneous abortion.
For paternal exposure, the total number of abortions in the studies with adequate exposure contrast were 340 for lead, 240 for mercury, and 90 for unspecified metals and, correspondingly, for maternal exposure, about 80 for lead, 80 for mercury, 70 for nickel, and 130 for exposure to unspecified metals. mercury, 70 studies indicate that paternal exposure to lead or mercury might be associated with the risk of spontaneous abortion.
For maternal exposure, no clear conclusion could be reached.
In particular, paternal occupational exposure levels to metals were substantial compared with population values.
Even though there are shortcomings in the present knowledge, protective goals for paternal exposure to lead and mercury are warranted.
More well-designed studies on metals are needed.
Mots-clés Pascal : Plomb, Métal lourd, Toxicité, Gestation pathologie, Homme, Epidémiologie, Finlande, Europe, Exposition professionnelle, Traitement père, Traitement mère, Avortement, Reproduction pathologie
Mots-clés Pascal anglais : Lead, Heavy metal, Toxicity, Pregnancy disorders, Human, Epidemiology, Finland, Europe, Occupational exposure, Paternal treatment, Maternal treatment, Abortion, Reproduction diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0496521
Code Inist : 002B03L05. Création : 01/03/1996.