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  1. Validity aspects of exposure and outcome data in reproductive studies.

    Article - En anglais

    Some validity aspects related to various sources on pregnancy outcome and exposure are discussed.

    Register-based data on outcome and exposure are compared with workers'own reports.

    The problems in the use of personal interview data on pregnancies are related to the possible selection in recognition and reporting the pregnancy outcome.

    The best way of avoiding misclassification of outcome is to resort to medical records whenever possible.

    Misclassification of exposure is most likely a common reason for discrepancies in results in reproductive studies.

    The misclassification of exposure deflates the power of the study to detect the true difference between exposed and nonexposed subjects, particularly when the prevalence of exposure is low.

    It is of great importance to confirm, if possible, the exposure status by using two or more independent sources of data.

    Mots-clés Pascal : Femme, Méthode étude, Validité, Gestation, Biais méthodologique, Questionnaire, Registre, Exposition professionnelle, Collecte donnée, Spécificité, Homme, Reproduction pathologie

    Mots-clés Pascal anglais : Woman, Investigation method, Validity, Pregnancy, Methodological bias, Questionnaire, Register, Occupational exposure, Data gathering, Specificity, Human, Reproduction diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0496498

    Code Inist : 002B30A03B. Création : 01/03/1996.