The prevalence of anti-Legionella pneumophila serogroup 1 antibodies in 777 blood donors of the Turin area was determined by the indirect immunofluorescence assay (IFA) and by the microagglutination test (MA).
Low titers (IFA of 1/16 and MA of 1/8) were found in 0.3% of the subjects.
A statistically significant difference was not observed by sex and by age for IFA titers, but was noted by sex for MA titers of = 1/4 (p<0.05).
The upper limit of normal titer was<1/8 by IFA and<1/4 by MA at 15% cutoff level and 1/8 by IFA and 1/4 by MA at 1% cutoff level.
In conclusion, the prevalence of antibodies in the Turin area was very low ; IFA titers of = 1/64 and MA titers of>1/16 can be considered as presumptive of infection in a single serum specimen of a patient with pneumonia ; no change in the epidemiology of the disease was observed in the recent years.
Mots-clés Pascal : Légionellose, Bactériose, Infection, Legionella pneumophila, Legionellaceae, Bactérie, Epidémiologie, Sérologie, Prévalence, Donneur sang, Homme, Italie, Europe, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Legionellosis, Bacteriosis, Infection, Legionella pneumophila, Legionellaceae, Bacteria, Epidemiology, Serology, Prevalence, Blood donor, Human, Italy, Europe, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0487293
Code Inist : 002B05B02E. Création : 01/03/1996.