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  1. Quantitative and qualitative distribution of mercury in organs from Arctic sledgedogs : an atomic absorption spectrophotometric and histochemical study of tissue samples from natural long-termed high dietary organic mercury-exposed dogs from Thule, Greenland.

    Article - En anglais

    Organs from 10 sledgedogs fed methyl mercury-containing organs and meat from predatory marine animals also eaten by humans in the Thule district of Greenland, were examined histochemically for cellular distribution of mercury, and the organ concentrations of mercury were quantified by atomic absorption spectrometry (total Hg).

    In selected organs the methyl mercuric level was determined by gaschromatography.

    The highest concentration of total mercury was found in mesenterial lymph nodes followed by liver and kidneys, which indicates that the lymphatic system might play an important role in the regulating transport of mercury to target organs.

    The concentrations were age-related. and the results suggest that demethylation takes place in all organs except skeletal muscles, but lowest in CNS.

    The distribution of mercury at cellular and subcellular levels was studied by the autometallographic technique.

    The atomic absorption spectrometric and autometallographic results were in good agreement.

    The brain mean concentration in the oldest group was 438 mug/kg, a level much lower than what has been reported to cause effects in the human central nervous system.

    However, if humans over a period of e.g. 50 years eat Arctic marine meat and accumulate mercury in the same way as dogs, the possibility that this may have health implications cannot be entirely excluded.

    Mots-clés Pascal : Mercure, Arctique, Animal, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Tissu, Analyse qualitative, Analyse quantitative, Distribution, Alimentation, Milieu aquatique, Chaîne alimentaire, Métal lourd, Méthylmercure

    Mots-clés Pascal anglais : Mercury, Arctic Region, Animal, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Tissue, Qualitative analysis, Quantitative analysis, Distribution, Feeding, Aquatic environment, Trophic chain, Heavy metal

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0486268

    Code Inist : 002B03L05. Création : 01/03/1996.