Paired samples of saliva and serum from 286 high-risk subjects were tested for HIV using two commercial enzyme immunoassays following the same WHO testing strategy supplemented with a Western blot technique.
Agreement between HIV testing in both sample types was 98.9% (95% confidence interval : 97.7-100).
The sensitivity of an EIA (Well-cozyme GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7% (151/153).
These results support previous data showing that in some situations saliva might be an effective alternative to serum for HIV testing.
Mots-clés Pascal : SIDA, Virose, Infection, Dépistage, Salive, Evaluation performance, Spécificité, Sensibilité, Anticorps, Surveillance sanitaire, Homme, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Medical screening, Saliva, Performance evaluation, Specificity, Sensitivity, Antibody, Sanitary surveillance, Human, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0484538
Code Inist : 002B06D01. Création : 01/03/1996.