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  1. Cost-effectiveness of clozapine treatment in therapy-refractory schizophrenia.

    Article - En anglais

    The costs and effects of clozapine treatment of refractory schizophrenic patients have been discussed recently.

    This study shows that 18 months of clozapine treatment results in an improvement of symptoms and social functioning in approximately 70% of treatment-refractory schizophrenic patients, compared with treatment with conventional neuroleptics during a similar period of time.

    Treatment with clozapine reduces the cost of inpatient care but places increased demands on active rehabilitation resources in outpatient care.

    This leads to increased total costs in a short-term perspective, but clozapine treatment is cost-saving for annual maintenance therapy.

    These costs must be weighed against the positive effects on psychotic symptoms and social functioning.

    Mots-clés Pascal : Schizophrénie, Psychose, Clozapine, Neuroleptique, Psychotrope, Chimiothérapie, Efficacité traitement, Analyse avantage coût, Etude longitudinale, Homme

    Mots-clés Pascal anglais : Schizophrenia, Psychosis, Neuroleptic, Psychotropic, Chemotherapy, Treatment efficiency, Cost benefit analysis, Follow up study, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0476856

    Code Inist : 002B02B03. Création : 01/03/1996.