The relation between esophageal cancers and head and neck tumors was studied in order to improve the treatment results in patients with multiple cancers.
We reviewed the records of 3,375 patients with an indexed squamous cell carcinoma of the head and neck treated at our institution between 1960 and 1994 ; and 81 patients were found to have an associated esophageal carcinoma.
Similarly, the records of 434 patients with an indexed esophageal cancer were reviewed ; and 54 patients had cancers in other organs or in the residual esophagus.
A total of 135 esophageal cancers with 154 synchronous or metachronous cancers were entered into the analysis.
The risk of developing esophageal cancer was ten times higher in male patients with head and neck cancer than in female patients.
Synchronous or metachronous esophageal cancer associated with head and neck cancer was most frequently seen with pharyngeal cancer (28/360=7.8%), followed by in the oral cavity (47/2148=2.2%). Conclusions.
Better knowledge of the relation between an esophageal cancer and a head and neck cancer may lead to the early detection of subsequent small, potentially curable neoplasms sited in either the esophagus or the head and neck region.
Cancer 1995 ; 76 : 101-5.
Mots-clés Pascal : Epithélioma, Oesophage, Association, Tête cou, Homme, Second cancer, Epidémiologie, Incidence, Analyse risque, Appareil digestif pathologie, Oesophage pathologie, Tumeur maligne, ORL pathologie
Mots-clés Pascal anglais : Carcinoma, Esophagus, Association, Head and neck, Human, Second cancer, Epidemiology, Incidence, Risk analysis, Digestive diseases, Esophageal disease, Malignant tumor, ENT disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0475484
Code Inist : 002B13A01. Création : 01/03/1996.