Dioxins are among the most toxic anthropogenic chemicals in the environment.
Their toxicity has been extensively studied in both humans and animals.
Dioxin-contaminated soil may result in dioxins occurring in a food chain.
This is especially important for the general population.
It has been estimated that about 98% of exposure to dioxins is through the oral route.
In the 1980s, a concentration level of 1 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in soil was specified as « a level of concern, » based on cancer effects.
However, recent studies indicate that end points other than cancer are also of concern.
A health risk analysis scenario based on health effects of TCDD other than cancer is discussed and compared with the projected intake from 1 ppb TCDD in soil.
Mots-clés Pascal : Dibenzo-p-dioxine(polychloro), Polluant, Environnement, Toxicité, Homme, Sol, Chaîne alimentaire, Contamination, Aliment, Evaluation, Risque, Relation dose réponse, Inhalation, Voie orale, Dose sans effet
Mots-clés Pascal anglais : Pollutant, Environment, Toxicity, Human, Soils, Trophic chain, Contamination, Food, Evaluation, Risk, Dose activity relation, Inhalation, Oral administration, No observed effect level
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0473142
Code Inist : 002B03M01. Création : 01/03/1996.