Based on notifications to the Danish Committee on Adverse Drug Reactions and to the Central Death Register, 30 cases of fatal drug-induced anaphylactic shock were identified during the period 1968-1990.
The most frequent causes were contrast media for X-ray examinations, antibiotics, and extracts of allergens.
Nine cases occurred outside hospital ; they were mainly caused by the use of allergen extracts of moulds for desensitization in general practice.
Fatal drug-induced anaphylactic shock is rare, estimated in the present study at 0.3 case per million inhabitants per year.
Mots-clés Pascal : Médicament, Toxicité, Pharmacovigilance, Anaphylaxie, Mort, Epidémiologie, Danemark, Europe, Homme, Allergie, Immunopathologie
Mots-clés Pascal anglais : Drug, Toxicity, Pharmacovigilance, Anaphylaxis, Death, Epidemiology, Denmark, Europe, Human, Allergy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0461127
Code Inist : 002B02U10. Création : 01/03/1996.