Proxy exposure measures and readily available data from the Wisconsin Cancer Reporting System were used to contrast 167 osteosarcoma cases with 989 frequency-matched cancer referents reported during 1979-1989.
Differences in potential exposure to water-borne radiation and fluoridated drinking water, population size for the listed place of residence, and seasonality were assessed.
An association was found between osteosarcoma and residence in a population of less than 9 000 (odds ratio=1.6,95% confidence interval=1.1-2.4).
In addition, an association between month of birth (May through July versus other months of birth) and osteosarcoma among individuals who were less than 25 y of age (odds ratio=1.9,95% confidence interval=1.1-3.4).
Overall, no association was found between potential exposure to fluoridated drinking water and osteosarcoma (odds ratio=1.0,95% confidence interval=0.6-1.5).
The association between osteosarcoma and water-borne radiation was weak and was not significant statistically (odds ratio=1.5,95% confidence interval=0.8-2.8).
Mots-clés Pascal : Epidémiologie, Tumeur maligne, Homme, Ostéosarcome, Wisconsin, Etats Unis, Amérique du Nord, Amérique, Fluorure, Polluant, Environnement, Variation saisonnière, Os, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Epidemiology, Malignant tumor, Human, Osteosarcoma, Wisconsin, United States, North America, America, Fluorides, Pollutant, Environment, Seasonal variation, Bone, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0453828
Code Inist : 002B15C. Création : 01/03/1996.