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  1. Screening for congenital hypothyroidism in Turkey.

    Article - En anglais

    A pilot study was performed to determine the incidence of congenital hypothyroidism (CH) in Turkey and to build a model for nationwide screening.

    From December 1991 to December 1992,30097 newborns were screened for CH using a primary measurement of thyroid stimulating hormone in capillary blood on days 3-5 of life.

    Samples were obtained in collaboration with the ongoing nationwide phenylketonuria screening programme.

    Eleven cases of primary CH were detected giving the incidence of 1 : 2736.

    Recall rate was 2.3%. Replacement therapy with L-thyroxine was started after the confirmation of diagnosis.

    The median age at the initiation of replacement therapy was 23 days (range 7-35 days).

    Conclusion The incidence of CH is notably higher in Turkey than reported in most other countries.

    Iodine deficiency and/or dyshormonogenesis might contribute to this high incidence.

    This result emphasizes the necessity of a nationwide screening programme.

    Mots-clés Pascal : Hypothyroïdie, Congénital, Nouveau né, Homme, Dépistage, Turquie, Asie, Epidémiologie, Incidence, Endocrinopathie, Thyroïde pathologie, Maladie congénitale

    Mots-clés Pascal anglais : Hypothyroidism, Congenital, Newborn, Human, Medical screening, Turkey, Asia, Epidemiology, Incidence, Endocrinopathy, Thyroid diseases, Congenital disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0439203

    Code Inist : 002B20G03. Création : 01/03/1996.