To investigate the predictive value of atopy, smoking, and living in a farm environment in the development of chronic bronchitis.
Design This was a cross sectional and longitudinal study.
Postal surveys carried out in Finland in 1975 and 1981.
The study was part of the Finnish twin cohort study, which included adult twin pairs born in Finland before 1958.
The cross sectional sample consisted of 18 351 subjects, including 1025 prevalent cases, and the follow up sample comprised 17 134 subjects, 553 of whom were incident cases of chronic bronchitis.
According to the cross sectional data, chronic bronchitis was associated with atopy (relative risk 1.41) and smoking (2.43).
In the follow up data, chronic bronchitis was related to atopy (1.28), smoking (2.31), and farming (1.45).
The results confirm the earlier finding in the Finnish farming population that, in addition to smoking, atopy predisposes the development of chronic bronchitis.
A farm environment was also found to be a predisposing factor.
The results give further support to the « Dutch hypothesis » on the aetiology of chronic bronchitis, according to which atopy is a predisposing factor.
Mots-clés Pascal : Bronchopneumopathie obstructive, Epidémiologie, Homme, Atopie, Activité professionnelle, Agriculture, Age, Sexe, Finlande, Europe, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Immunopathologie, Allergie
Mots-clés Pascal anglais : Obstructive pulmonary disease, Epidemiology, Human, Atopy, Professional activity, Agriculture, Age, Sex, Finland, Europe, Respiratory disease, Lung disease, Bronchus disease, Immunopathology, Allergy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0424571
Code Inist : 002B11B. Création : 01/03/1996.