Prevalence of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 infection among Spanish drug users measured by HTLV-1 assay and HTLV-1 and - 2 assay.
The prevalence of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 infection in 1992 and 1993 was determined by testing 2,152 specimens from injection drug users living in 11 geographic areas of Spain.
Results obtained by an authentic HTLV-1 and - 2 test were compared with those obtained by an HTLV-1 assay.
HTLV infection was identified in 7 of 11 regions, with an overall prevalence of 2.5% (range, 0.4 to 11.5%). Fourty-four (81%) of 54 subjects were infected with HTLV-2 ; the viral strains in the remaining 10 subjects could not be serologically typed.
Underestimation of HTLV infection because of the low sensitivities of HTLV-1 enzyme immunoassays for HTLV-2 antibody was relatively low (<20%). Therefore, previous epidemiologic findings generated with HTLV-1 enzyme immunoassays appear to be reasonably accurate.
Our results suggest that the rate of HTLV infection may have been increasing recently among Spanish drug users.
Mots-clés Pascal : Virus HTLV1, Retroviridae, Virus, Virus HTLV2, Virose, Infection, Prévalence, Homme, Toxicomanie, Espagne, Europe, Epidémiologie
Mots-clés Pascal anglais : HTLV-I virus, Retroviridae, Virus, HTLV-II virus, Viral disease, Infection, Prevalence, Human, Drug addiction, Spain, Europe, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0422860
Code Inist : 002B05C02D. Création : 01/03/1996.