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  1. Prevalence of antibodies to human T-hymphotrophic virus types I and II in volunteer blood donors and high-risk groups in northwestern Greece.

    Article - En anglais

    Background 

    In addition to human immunodeficiency virus, human T-lymphotropic virus types I and II (HTLV-I/II) is prevalent among blood donors in the United States.

    In Greece, there are no epidemiologic data regarding the prevalence of HTLV-I/II among volunteer blood donors and high-risk groups.

    Study Design and Methods 

    To determine the prevalence of HTLV-I/II infections in northwestern Greece, a seroepidemiologic study was conducted among volunteer blood donors, multiply transfused patients, heroin addicts, and chronic hemodialysis patients.

    The subjects were tested for serologic evidence of HTLV-I/II infection by enzyme immunoassays and specific protein immunoblot confirmatory test.

    Results 

    None of the volunteer blood donors and heroin addicts had detectable antibodies to HTLV-I/II.

    Only 1 (1.45%) of the 69 multiply transfused patients had indeterminate results, while 2 (1.2%) of 163 hemodialysis patients were positive.

    Conclusion 

    In northwestern Greece, routine screening for HTLV-I and HTLV-II infections does not appear to be required.

    However, the finding of seropositivity among hemodialysis patients requires further evaluation of the origin of the infection, as its zero prevalence in this population seems to exclude transfusion transmission.

    Mots-clés Pascal : Anticorps, Virus HTLV1, Retroviridae, Virus, Virus HTLV2, Donneur sang, Grèce, Europe, Prévalence, Homme, Sérologie

    Mots-clés Pascal anglais : Antibody, HTLV-I virus, Retroviridae, Virus, HTLV-II virus, Blood donor, Greece, Europe, Prevalence, Human, Serology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0414844

    Code Inist : 002B27D01. Création : 01/03/1996.