First admission psychiatric patients born in England and Wales between 1938 and 1963, and discharged from hospitals in England and Wales between 1976 and 1986, were examined.
Using logistic regression, we tested the hypothesis that the risk of shizophrenia varies by place, and season of birth.
Persons born in city areas showed a 12% greater risk of schizophrenia (odds ratio 1.12 ; 95% confidence interval 1.06 to 1.19) than those born in non-city areas, when compared with other psychiatric patients.
The increase in risk was particularly high for individuals born in city areas in winter (21%, ie odds ratio 1.21 and confidence interval 1.08 to 1.36).
These findings suggest that the factor (s) responsible for the season-of-birth effect preferentially affects city born schizophrenics.
Mots-clés Pascal : Facteur risque, Schizophrénie, Psychose, Variation saisonnière, Variation géographique, Angleterre, Grande Bretagne, Royaume Uni, Europe, Pays de Galles, Milieu urbain, Epidémiologie, Santé mentale, Homme
Mots-clés Pascal anglais : Risk factor, Schizophrenia, Psychosis, Seasonal variation, Geographical variation, England, Great Britain, United Kingdom, Europe, Wales, Urban environment, Epidemiology, Mental health, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0399086
Code Inist : 002B18C06A. Création : 01/03/1996.