The risk for transmission of Mycobacterium tuberculosis at the bedside and during autopsy.
To emphasize the differing infectious potentials of a patient with tuberculosis.
Hospital ward and autopsy room.
An epidemiologic investigation of tuberculin skin test conversions in a clinical setting and during autopsy when results of tuberculin tests done before exposure were available for all participants.
Tuberculin skin test results after the discovery of tuberculosis exposure from a patient with unsuspected tuberculosis for comparison with the test results before exposure ; culture of sputum and autopsy material for Mycobacterium tuberculosis ; and DNA fingerprinting of organisms.
Preventive therapy for persons with skin test conversion.
None of the 40 skin test-negative health care workers caring for the patient for 3 weeks on an open medical ward showed a skin test conversion, even though they had not used respiratory precautions.
By contrast, among personnel present during the 3-hour autopsy, the test results of all five nonreactors converted from negative to positive (mean reaction, 24 mm).
Two of these persons had a positive sputum culture 8 weeks later.
The DNA fingerprints of all three isolates were identical.
A patient who did not transmit tuberculosis before death released a prodigious number of tubercle bacilli during autopsy.
Mots-clés Pascal : Tuberculose, Poumon, Risque infectieux, Travailleur, Hôpital, Autopsie, Mycobacterium tuberculosis, Epidémiologie, Homme, Mycobactériose, Bactériose, Infection, Mycobacteriaceae, Mycobacteriales, Actinomycetes, Bactérie, Appareil respiratoire pathologie, Poumon pathologie
Mots-clés Pascal anglais : Tuberculosis, Lung, Infectious risk, Worker, Hospital, Autopsy, Mycobacterium tuberculosis, Epidemiology, Human, Mycobacterial infection, Bacteriosis, Infection, Mycobacteriaceae, Mycobacteriales, Actinomycetes, Bacteria, Respiratory disease, Lung disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0397150
Code Inist : 002B30A01C. Création : 01/03/1996.