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  1. Intractable diarrhoea in infancy in the 1990s : a survey in Italy.

    Article - En anglais

    A « quick » prevalence study of intractable diarrhoea (defined as diarrhoea lasting more than 3 weeks and dependent on parenteral nutrition [PN] for more than 50% of daily caloric intake) was conducted by FAX.

    All 35 paediatric gastroenterology services which had been contacted answered questionnaire sent by FAX. 20 cases of intractable diarrhoea were identified in 9 centres.

    In 12 cases PN was administered at home, the other 8 cases being treated as inpatients for an average duration of 9.5 months.

    A diagnosis had been established in 11 out of 20 cases.

    Auto-immune enteropathy was the most frequent diagnosis (5 cases) ; congenital microvillous atrophy (3 cases) ; chronic pseudo-obstruction (2 cases) and multiple food intolerance (1 case).

    Undefinied 9/20 cases presented atrophy of intestinal mucosa.

    The age of the beginning of diarrhoea varied from 2 days to 12 years, but was more than 16 months only in some cases with auto-immune enteropathy.

    Conclusion :

    Intractable diarrhoea has a low prevalence in Italy and remains a rare but very intricating problem.

    Long-term PN is recommended in most cases : autoimmune enteropathy is the most frequent cause but in about half of the cases the aetiopathogenetic diagnosis is still not defined.

    Mots-clés Pascal : Diarrhée, Chronique, Nourrisson, Homme, Epidémiologie, Italie, Europe, Etiologie, Traitement, Nutrition, Voie parentérale, Appareil digestif pathologie, Intestin pathologie

    Mots-clés Pascal anglais : Diarrhea, Chronic, Infant, Human, Epidemiology, Italy, Europe, Etiology, Treatment, Nutrition, Parenteral administration, Digestive diseases, Intestinal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0384343

    Code Inist : 002B13B03. Création : 01/03/1996.