The objectives were to describe and discuss the current and proposed European occupational health policy on two categories of substances that pose serious effects : those potentially carcinogenic or genotoxic and those with toxic effects on reproduction.
The precautionary principle was applied to setting standards for the workplace for those two categories of substances, to give an impression of the resulting limit values and the consequences of the implementation of this precautionary principle.
A pragmatic approach was chosen as this starts with substantial indications of health risks.
For the suspected carcinogenic or genotoxic substances 0.1 mg/m3 as a precautionary occupational exposure limit (precautionary OEL) is proposed.
For the substances suspected of causing reproductive toxicity the precautionary OEL was derived in three ways, depending on the availability of data and of a current Dutch workplace standard (MAC, maximum accepted concentration) :
(a) by calculation based on available inhalatory animal data on the risks of reproductive toxicity ;
(b) by adding a safety factor of 10 to the current MAC, if no inhalatory animal data on reproductive toxicity are available ;
(c) by using 0.1mg/m3 as precautionary OEL for substances suspected of having reproductive toxicity but without inhalatory animal data on reproductive toxicity and without a MAC.
Mots-clés Pascal : Politique sanitaire, Union européenne, Composé chimique, Toxicité, Gestation, Nouveau né pathologie, Foetus pathologie, DNA, Carcinogène, Exposition professionnelle, Milieu professionnel, Normalisation, Concentration maximale admissible, Médecine travail, Législation
Mots-clés Pascal anglais : Health policy, European Union, Chemical compound, Toxicity, Pregnancy, Newborn diseases, Fetal diseases, DNA, Carcinogen, Occupational exposure, Occupational environment, Standardization, Maximum permissible concentration, Occupational medicine, Legislation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0377217
Code Inist : 002B30B03. Création : 01/03/1996.