Environmental and biological monitoring of occupational exposure to 1,1,1-trichloroethane.
Fifty workers involved in various degreasing and cleaning processes using 1,1,1-trichloroethane (1,1,1-TCE) were studied with respect to personal and static exposures.
In addition, end-of-shift expired air and venous blood samples were taken for analysis of the parent compound.
Urinary samples were also obtained at the same time for analysis of its metabolites - trichloroethanol (TCOH) and trichloroacetic acid (TCA).
The results show that open/manual degreasing processes generate the highest environmental solvent levels (mean=819.9 mg/m3 ; SD=781.9 mg/m3) followed by jet-spray cleaning (mean=460.5 mg/m3 ; SD=292.4 mg/m3), vapour degreasing (mean=365.3 mg/m3 ; SD=279.9 mg/m3) and ultrasonic degreasing (mean=134.7 mg/m3 ; SD=121.0 mg/m3).
Personal exposure levels were well correlated with concentrations of 1,1,1 - TCE in end-of-shift expired air (r=0.81) and venous blood samples (r=0.88) but only moderately correlated with concentrations of its metabolites in urine (r=0.49 for TCOH ; r=0.58 for TCA).
Static (area) samples were poorly correlated with the biological exposure indices studied.
Mots-clés Pascal : Solvant organique, Exposition professionnelle, Homme, Dégraissant, Produit nettoyage, Relation dose réponse, Surveillance biologique, Contrôle, Teneur air ambiant, Lieu travail, Procédé, Médecine travail, Ethane(1,1,1-trichloro)
Mots-clés Pascal anglais : Organic solvent, Occupational exposure, Human, Degreasing agent, Cleaning materials, Dose activity relation, Biological monitoring, Check, Ambient air concentration, Work place, Operating process, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0367224
Code Inist : 002B03L04. Création : 01/03/1996.