logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Racial differences in the incidence of gout : the role of hypertension.

    Article - En anglais

    Objective

    To estimate the incidence of and examine risk factors for the development of gout in black and white male physicians.

    Methods

    Data from 2 cohorts of former medical students, 352 black men in the Meharry Cohort Study and 571 white men in the Johns Hopkins Precursors Study, were analyzed.

    Cases of gout were identified by self-report.

    Baseline variables and incident hypertension were examined as risk factors for the development of gout in both cohorts.

    Results

    The incidence of gout was 3.11 and 1.82 per 1,000 person-years in the black men and the white men, respectively (P<0.05) ; the cumulative incidence was 10.9% and 5.8%, respectively (P=0.04).

    The relative risk (RR) for gout among the black men was 1.69 (95% confidence interval [95% CI] 1.02-2.80).

    This excess risk persisted after adjustment for baseline systolic blood pressure (adjusted RR=1.96 [95% CI 1.14-3.38]). Incident hypertension was independently associated with the development of gout in univariate analysis (RR=3.78 [95% Cl 2.18-6.58]) ; when this variable was included as a time-dependent covariate in a Cox model, the excess risk for gout in black men was reduced and no longer significant (adjusted RR=1.30 [95% CI 0.77-2.19]). Conclusion.

    The approximately 2-fold excess risk for gout among black men is explained, in part, by a greater risk of incident hypertension.

    Mots-clés Pascal : Goutte(pathologie), Homme, Facteur risque, Epidémiologie, Etude comparative, Etats Unis, Amérique du Nord, Amérique, Ethnie, Mâle, Caucasoïde, Négroïde, Hypertension artérielle, Microcristal, Urique acide, Métabolisme pathologie, Hyperuricémie, Système ostéoarticulaire pathologie, Arthropathie, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Gout, Human, Risk factor, Epidemiology, Comparative study, United States, North America, America, Ethnic group, Male, Caucasoid, Negroid, Hypertension, Microcrystal, Uric acid, Metabolic diseases, Hyperuricemia, Diseases of the osteoarticular system, Arthropathy, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0354945

    Code Inist : 002B22E01. Création : 01/03/1996.