The relationship of vitamin A deficiency and child survival has been documented in a number of studies but not in others, yet the relationship of vitamin A with child morbidity remains controversial.
We prospectively examined the relationship of dietary vitamin A intake and the incidences of diarrhea and respiratory infection among 28,753 Sudanese children between the ages of 6 mo and 6 y. Total dietary vitamin A intake was strongly and inversely associated with the risk of diarrhea (multivariate risk in top relative to bottom quintile=0.58,95% confidence interval=0.47-0.72) ; we also observed a strong inverse association with the risk of having cough and fever (0.60,0.45-0.81).
On the other hand, we noted a significantly positive association of dietary vitamin A intake and incidence of cough alone (1.69,1.52-1.88), a sign that may be associated with a healthy respiratory epithelium.
Vitamin A intake was also negatively associated with the risk of measles.
These prospective data emphasize the importance of adequate dietary vitamin A intake to protect the health of children in developing countries.
Mots-clés Pascal : Carence vitaminique, Etat nutritionnel, Rétinol, Morbidité, Facteur risque, Infection, Appareil respiratoire pathologie, Diarrhée, Rougeole, Virose, Epidémiologie, Malnutrition, Vitamine, Enfant, Homme, Soudan, Afrique
Mots-clés Pascal anglais : Vitamin deficiency, Nutritional status, Retinol, Morbidity, Risk factor, Infection, Respiratory disease, Diarrhea, Measles, Viral disease, Epidemiology, Malnutrition, Vitamin, Child, Human, Sudan, Africa
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0346527
Code Inist : 002B22C. Création : 01/03/1996.