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  1. Recent trends in mortality from peptic ulcer disease in Finland.

    Article - En anglais

    The enormous change of medical therapy of peptic ulcer disease in the 1970s has resulted in a significant decrease of elective ulcer surgery.

    It has been speculated whether this might be reflected in the mortality of the disease.

    Therefore, in the present study, the mortality rate of the disease was evaluated in Finland during the past 17 years covering the dramatic change in the medical therapy : the introduction of H2-receptor antagonists.

    This was done with a population-based epidemiological study by analyzing 1262 death certificates of people dying from peptic ulcer disease in Finland between 1972 and 1989.

    The study showed that there has been almost twofold increase in the mortality of the disease between 1972 and 1989 in Finland.

    This was mainly due to the significantly increased number of fatal ulcer hemorrhages in older people, but also mortality from ulcer perforations increased.

    This unfavorable epidemiological progress was most striking among elderly women and became manifest during the 1980s.

    We conclude that mortality from peptic ulcer disease has significantly increased in Finland due to fatal ulcer hemorrhages and perforations.

    This epidemiological change became manifest in the 1980s, concurrently with the dramatic change in the medical therapy of peptic ulcer disease.

    Mots-clés Pascal : Ulcère, Estomac, Epidémiologie, Mortalité, Influence, Chimiothérapie, Etude temporelle, Homme, Finlande, Europe, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Ulcer, Stomach, Epidemiology, Mortality, Influence, Chemotherapy, Temporal study, Human, Finland, Europe, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0271525

    Code Inist : 002B13B03. Création : 01/03/1996.