To determine the incidence of acute symptomatic toxoplasma retinochoroiditis presenting to ophthalmologists for patients born in Britain and elsewhere.
Setting-11 districts in south Greater London.
Subjects-All patients presenting to NHS ophthalmologists with symptoms due to acute toxoplasma retinochoroiditis in 1992-3.
Main outcome measure-Intraocular inflammation in association with a retinochoroidal scar, active adjoining retinitis, and IgG serum antibodies to toxoplasma.
The estimated incidence of acute symptomatic retinochoroiditis for all people born in Britain was 0.4/100000/year and for black people born in west Africa 57/100000/year.
If a mean of two symptomatic episodes per lifetime is assumed, 100 people born in Britain may be affected each year, about a fifth of the estimated 500-600 congenitally infected people born each year.
Conclusions-A substantial proportion of people with acute symptomatic toxoplasma retinochoroiditis were born outside the country, and the number born in Britain was smaller than the number previously estimated to develop retinochoroidal lesions due to congenital toxoplasmosis.
These findings suggest that prenatal screening for toxoplasmosis in Britain may be of limited benefit.
Mots-clés Pascal : Rétinopathie, Choroïdite, Toxoplasmose, Protozoose, Parasitose, Infection, Congénital, Aigu, Oeil pathologie, Rétinite, Lieu naissance, Incidence, Prévalence, Evaluation, Dépistage, Prénatal, Prévention, Analyse avantage coût, Angleterre, Grande Bretagne, Royaume Uni, Europe
Mots-clés Pascal anglais : Retinopathy, Choroiditis, Toxoplasmosis, Protozoal disease, Parasitosis, Infection, Congenital, Acute, Eye disease, Retinitis, Birth place, Incidence, Prevalence, Evaluation, Medical screening, Prenatal, Prevention, Cost benefit analysis, England, Great Britain, United Kingdom, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0266941
Code Inist : 002B09I. Création : 01/03/1996.