Trends in survival after childhood cancer in Denmark, 1943-87 : a population-based study.
Survival from cancer in childhood and adolescence was studied in a population-based series of 8312 cases in children aged 0-19 years notified to the Danish Cancer Registry during 1943-87.
During the first period (1943-72), 5-year survival rates from all malignant neoplasms increased from 23% (1943-52) to 33% (1963-72).
The greatest improvement was seen during the period 1973-87 when 5-year survival rates reached 64% (1983-87).
Between 1973-77 and 1983-87,5-year survival rates increased from 32% to 62% for leukaemia, from 40% to 70% for acute lymphoblastic leukaemia, from 35% to 54% for non-Hodgkin's lymphoma, from 50% to 66% for central nervous system neoplasms and from 25% to 49% for bone tumours.
An improvement in 5-year survival rates from Wilms'tumour was seen between 1960 (19%) and 1980 (81%). Up to 1972, the 5-year survival rate from germ-cell neoplasms was approximately 40% ; among patients diagnosed in 1983-87,76% survived for 5-years.
Annual lethality decreased by 2.5% for all malignant neoplasms in 1943-72 and by 4.4% in 1972-87.
Lethality was similar for boys and girls during the period 1943-72, but was significantly lower for girls subsequently.
A marked effect of age at diagnosis was seen in the early registration period, where lethality rate for the age group 0-9 years was substantially higher compared with that in the age group 10-19 years.
This inequality persisted only for children less than 2 years of age at the time of diagnosis in the later period.
Mots-clés Pascal : Tumeur maligne, Hémopathie maligne, Enfant, Homme, Adolescent, Epidémiologie, Mortalité, Danemark, Europe, Survie
Mots-clés Pascal anglais : Malignant tumor, Malignant hemopathy, Child, Human, Adolescent, Epidemiology, Mortality, Denmark, Europe, Survival
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0252434
Code Inist : 002B04B. Création : 01/03/1996.