Socioeconomic status and colon cancer incidence : a prospective cohort study.
The association between socioeconomic status and colon cancer was investigated in a prospective cohort study that started in 1986 in The Netherlands among 120 852 men and women aged 55-69 years.
At baseline, data on socioeconomic status, alcohol consumption and other dietary and non-dietary covariates were collected by means of a self-administered questionnaire.
For data analysis a case-cohort approach was used, in which the person-years at risk were estimated using a randomly selected subcohort (1688 men and 1812 women).
AFter 3.3 years of follow-up, 312 incident colon cancer cases were detected : 157 men and 155 women.
AFter adjustment for age, we found a positive association between colon cancer risk and highest level of education (trend P=0.13) and social standing (trend P=0.008) for men.
Also, male, upper white-collar workers had a higher colon cancer risk than blue-collar workers (RR=1.42,95% CI 0.95-2.11).
Only the significant association between social standing and colon cancer risk persisted after additional adjustment for other risk factors for colon cancer (trend P=0.005), but the higher risk was only found in the highest social standing category (RR highest/lowest social standing=2.60,95% CI 1.31-5.14).
In women, there were no clear associations between the socioeconomic status indicators and colon cancer.
Mots-clés Pascal : Tumeur maligne, Côlon, Homme, Epidémiologie, Incidence, Niveau étude, Activité professionnelle, Statut socioéconomique, Age, Sexe, Pays Bas, Europe, Etude cohorte, Appareil digestif pathologie, Intestin pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Human, Epidemiology, Incidence, Education level, Professional activity, Socioeconomic status, Age, Sex, Netherlands, Europe, Cohort study, Digestive diseases, Intestinal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0250559
Code Inist : 002B13B01. Création : 01/03/1996.